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用途
Lexibulin(CYT-997)是微管蛋白聚集強(qiáng)效抑制劑，對多種癌細(xì)胞的IC50值為10-100nM，體外體內(nèi)具有高效的細(xì)胞毒性和血管增生阻斷作用。
1、產(chǎn)品物理參數(shù)：
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常用名
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N-乙基-N'-[2-甲氧基-4-[5-甲基-4-[[(1S)-1-(3-吡啶基)丁基]氨基]-2-嘧啶基]苯基]脲
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英文名
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Lexibulin
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CAS號
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917111-44-5
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分子量
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434.53
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密度
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1.2±0.1 g/cm3
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沸點(diǎn)
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557.7±50.0 °C at 760 mmHg
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分子式
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C24H30N6O2
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熔點(diǎn)
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無資料
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閃點(diǎn)
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291.1±30.1 °C
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2、物理化學(xué)性質(zhì)
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密度
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1.2±0.1 g/cm3
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沸點(diǎn)
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557.7±50.0 °C at 760 mmHg
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分子式
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C24H30N6O2
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分子量
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434.53
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閃點(diǎn)
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291.1±30.1 °C
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PSA
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107.78000
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LogP
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4.14
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蒸汽壓
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0.0±1.5 mmHg at 25°C
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折射率
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1.610
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3、英文別名
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S2195_Selleck
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Lexibulin (USAN)
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CYT997 (Lexibulin)
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Lexibulin
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N-[2-methoxy-4-(6-{[(1S)-1-pyridin-3-ylbutyl]amino}pyrazin-2-yl)phenyl]-N'-ethylurea
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Lexibulin [INN]
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N-ethyl-N'-[2-methoxy-4-(5-methyl-4-{[(1S)-1-pyridin-3-ylbutyl]amino}pyrimidin-2-yl)phenyl]urea
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1-Ethyl-3-[2-methoxy-4-(5-methyl-4-{[(1S)-1-(3-pyridinyl)pentyl]amino}-2-pyrimidinyl)phenyl]urea
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N-ethyl-N'-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)butyl]amino]-2-pyrimidinyl]phenyl]-urea
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N-ethyl-N'-[2-methoxy-4-(5-methyl-4-{[(1S)-1-(pyridin-3-yl)butyl]amino}pyrimidin-2-yl)phenyl]urea
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Lexibulin [USAN:INN]
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CYT997
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(S)-1-ethyl-3-(2-methoxy-4-(5-methyl-4-((1-(pyridin-3-yl)butyl)amino)pyrimidin-2-yl)phenyl)urea
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Urea, N-ethyl-N'-[2-methoxy-4-[5-methyl-4-[[(1S)-1-(3-pyridinyl)pentyl]amino]-2-pyrimidinyl]phenyl]-
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